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Single-Point Left Ventricular Pacing Optimized by ECG Results in Better Resynchronization than Multipoint Pacing
Single-Point Left Ventricular Pacing Optimized by ECG Results in Better Resynchronization than Multipoint Pacing
- Publication Year :
- 2020
- Publisher :
- Authorea, Inc., 2020.
-
Abstract
- Background: Multipoint pacing (MPP) in cardiac resynchronization therapy (CRT) activates the left ventricle from two locations, thereby shortening the QRS duration and enabling better resynchronization; however, compared with conventional CRT, MPP reduces battery longevity. On the other hand, electrocardiogram-based optimization using the fusion-optimized intervals (FOI) method achieves more significant reverse remodeling than nominal CRT programming. Our study aimed to determine whether MPP could attain better resynchronization than single-point pacing (SPP) optimized by FOI. Methods: This prospective study included 32 consecutive patients who successfully received CRT devices with MPP capabilities. After implantation, the QRS duration was measured during intrinsic rhythm and with three pacing configurations: MPP, SPP-FOI, and MPP-FOI. In 14 patients, biventricular activation times (by electrocardiographic imaging, ECGI) were obtained during intrinsic rhythm and for each pacing configuration to validate the findings. Device battery longevity was estimated at the 45-day follow-up. Results: The SPP-FOI method achieved greater QRS shortening than MPP (-56±16 vs. -42±17 ms, P
- Subjects :
- medicine.medical_specialty
business.industry
medicine.medical_treatment
Cardiac resynchronization therapy
Ventricular pacing
QRS complex
medicine.anatomical_structure
Ventricle
Internal medicine
Electrocardiographic imaging
medicine
Cardiology
cardiovascular diseases
Single point
Reverse remodeling
business
Subjects
Details
- Database :
- OpenAIRE
- Accession number :
- edsair.doi...........e691f3bd20a1ecd06a6272ff58ebb4b5
- Full Text :
- https://doi.org/10.22541/au.160193380.03603072/v1