Conformational difference in the solid state and in solution of methyl 2,3,4-trideoxy-2,4-di-C-methyl-6-O-trityl-α-d-lyxo-hexopyranoside

The conformational difference of the title compound ( 1 ) in the solid state and in solution has been investigated by X-ray crystallography and high-field proton n.m.r. spectrometry. In the solid state, compound 1 adopts the 4 C 1 ( d ) conformation ( 1a ), whereas 1 exists preferentially in the 1 C 4 ( d ) conformation ( 1b ) in chloroform solution.