Quantifying DNA damage on paper sensors via controlled template-independent DNA polymerization

Authors :: Wei Xue
Qiang Zhang
Yangyang Chang
John D. Brennan
Yingfu Li
Meng Liu
Source :: Chemical Science. 13:6496-6501
Publication Year :: 2022
Publisher :: Royal Society of Chemistry (RSC), 2022.
Abstract: Terminal deoxynucleotidyl transferase (TdT) catalyzes template-independent DNA synthesis in a well-controllable mode on paper, allowing absolute quantification of polymetric labeling of a single 3′-OH present on genomic DNA.

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