In hepatocellular carcinoma miR-494 up-regulates the AKT/mTOR pathway and is involved in Sorafenib resistance

Authors :: Luigi Bolondi
Laura Gramantieri
Daniela Pollutri
Francesca Fornari
Clarissa Patrizi
Manuela Ferracin
Sara Marinelli
Massimo Negrini
M. Baron Toaldo
Source :: Digestive and Liver Disease. 48:e28
Publication Year :: 2016
Publisher :: Elsevier BV, 2016.

Subjects :: 0301 basic medicine
Hepatology
business.industry
RPTOR
Gastroenterology
medicine.disease
Sorafenib resistance
03 medical and health sciences
030104 developmental biology
0302 clinical medicine
030220 oncology & carcinogenesis
Hepatocellular carcinoma
Cancer research
Medicine
business
Protein kinase B
PI3K/AKT/mTOR pathway

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