Lactols in stereoselection 1. Highly selective 1,4- and 1,5-asymmetric induction

Authors :: Katsuhiko Tomooka
Tatsuyuki Okinaga
Keisuke Suzuki
Gen ichi Tsuchihashi
Source :: Tetrahedron Letters. 28:6335-6338
Publication Year :: 1987
Publisher :: Elsevier BV, 1987.
Abstract: Nucleophilic addition to substituted γ- and δ-lactols with titanium reagents provides 1,4-syn and 1,5-syn diols in high stereoselectivity, which represents a new and simple method for the remote asymmetric induction.

Subjects :: Nucleophilic addition
Stereochemistry
Organic Chemistry
Diol
Highly selective
Biochemistry
Asymmetric induction
chemistry.chemical_compound
chemistry
Reagent
Drug Discovery
Hemiacetal
Stereoselectivity
Aliphatic compound

Tools