CHANGES IN CLINICAL CHARACTERISTICS AND BIOCHEMICAL INDICES OF FUR ANIMALS AND POULTRY BLOOD UNDER EIMERIA INVASION

The research has revealed the invasion agents like: Eimeria perforans, E. magna, E. stiedae in rabbits and nutrias, in a small amount– E. coecicola, E. pisiformis and E. intestinalis in rabbits, Е. maxima, E. tenella, E. necatrix and E. acervulina in chickens and quails. Rapidly infected fur animals (280 rabbits and 180 nutrias), 3468 chickens and 1800 quails were examined while conducting a research. Under the localization of a path-alogic process, the disease appeared in poultry in a mixed pattern; in rabbits and nutrias in an intestinal pat-tern (11.9 % and 11 %), in a hepatic pattern (8.1 % and 11 %) and mostly in a mixed pattern (80 % and 78 % respectively). The research showed that sick rabbits and nutrias were weak, mucous membranes of eyes and nose were pale (50.5 and 49 %), yellowish (38 and 42 %). Occasional watery feces (80 and 91 %), flatus were observed, the abdomen was increased and infirm (87.1 and 85 %). Under complications the rabbits had intermittent fever (5%), acute bouts of cramps (7.14 %). Death was observed in rabbits under a severe disease in two weeks time (10%) and in nutrias in 3-5 weeks (7%). Digestive unsets were a characteristic feature under an asymptomatic disease course. From among the blood biochemical indices of nutrias and rabbits, a decrease in the count of hemoglobu-line, in the amount of albumen, crude protein as compared to a control group was registered. A depressed state, thirst, (27th day), 1-2 ºС temperature rise, drowsiness, awkward gait (35th day), watery feces, feces with blood admixtures were registered in chickens, and the quails manifested unwillingness to eat, gathered in warm places, they also had white-and-green watery feces, labored respiration and accelerated cardiac rate. Some decrease in the amount of red blood cells, pseudoeosinophils as well as some increase in the amount of white blood cells and eosonophils were registered in the blood of sick chickens and quails. Some decrease in the count of hemoglobulin, in the amount of creatinine and urine was registered in blood serum of the infected chickens and quails. Thus, some changes in blood indices of chickens and quails which suffered from protozoal invasion testi-fied to a toxic and trophic effects of eimerias and their metabolites on the organisms.