Complex Numerical Processing for In-Focus Line-Field Spectral-Domain Optical Coherence Tomography

We propose a non-iterative deconvolution method that can improve the out-of-focus lateral resolution in line-field spectral-domain optical coherence tomography. By using an inverse filter designed from the point spread function of the system, the out-of-focus lateral resolution can be enhanced to a level comparable with the in-focus resolution over the entire axial measurement range. The resolution before and after this deconvolution has been verified experimentally. Furthermore, the method has been applied to the measurement of an ex vivo porcine eye chamber, which has demonstrated that the method was satisfactorily applicable to biomedical applications.