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Pneumococcal-vaccine-induced thrombocytopenia
- Source :
- JAMA: The Journal of the American Medical Association. 248:1178b-1178
- Publication Year :
- 1982
- Publisher :
- American Medical Association (AMA), 1982.
-
Abstract
- To the Editor.— Pneumococcal vaccine has been used to protect high-risk individuals from pneumococcal infection.1Both local and systemic adverse reactions have been described with the administration of this vaccine.2Kelton3described two patients with immune thrombocytopenia (ITP) who had relapses of their disease after receiving pneumococcal vaccine. This is another case report of the occurrence of thrombocytopenia in a patient with ITP after receiving this vaccine. Report of a Case.— A 17-year-old boy had a platelet count of 18,000/μL of two years' duration. A bone marrow examination disclosed increased megakaryocytes, and secondary causes of thrombocytopenia were excluded. A test for platelet-associated IgG was positive. A regimen of 60 mg/day of prednisone was begun. After an initial favorable response to prednisone administration, the platelet count fell to 40,000/μL. A splenectomy was performed five weeks after the initiation of prednisone therapy. On the day of splenectomy, the platelet
- Subjects :
- medicine.medical_specialty
medicine.diagnostic_test
business.industry
medicine.medical_treatment
Splenectomy
General Medicine
Disease
Gastroenterology
Immune thrombocytopenia
Bone marrow examination
Regimen
Pneumococcal vaccine
Prednisone
hemic and lymphatic diseases
Internal medicine
Immunology
medicine
Platelet
business
medicine.drug
Subjects
Details
- ISSN :
- 15383598 and 00987484
- Volume :
- 248
- Database :
- OpenAIRE
- Journal :
- JAMA: The Journal of the American Medical Association
- Accession number :
- edsair.doi...........ecf8ac42dc18470404f3ea7f555d0cbd
- Full Text :
- https://doi.org/10.1001/jama.248.10.1178b