An amazibg example of yin-yang aminolysis in cyclophosphazenes

Aminolysis of hexachlorocyrocyclotriphosphazene, N3P3Cl6, by the spermine-like derivative coded as SPM (323), namely N,N′-bis-(3-aminopropyl)-ethylendiamin H2N-(CH2)3-NH--(CH2)2-NH-(CH2)3-NH2, yields regiospecifically either to the DISPIRANSA or to the DISPIRBINO moiety depending on which chemical is used as the yin reactant. Indeed, if N3P3Cl6 is added as the yang active reactant to the tetramine as the yin passive receptor, the former configuration is obtained whereas the the latter proceeds from an addition of the tetraamine as the yang active reactant on the N3P3Cl6 as the yin receptor.