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Prenatal screening for congenital heart disease using real-time three-dimensional echocardiography and a novel ‘sweep volume’ acquisition technique

Prenatal screening for congenital heart disease using real-time three-dimensional echocardiography and a novel ‘sweep volume’ acquisition technique

Authors :
Greggory R. DeVore
R. K. Chang
David A. Miller
Grace C. Kung
Dolores H. Pretorius
Pierre C. Wong
Mark Sklansky
Source :
Ultrasound in Obstetrics and Gynecology. 25:435-443
Publication Year :
2005
Publisher :
Wiley, 2005.

Abstract

Objectives Conventional prenatal screening for congenital heart disease (CHD) involves a time-consuming and highly operator-dependent acquisition of the four-chamber view and outflow tracts. By acquiring the entire fetal heart instantaneously as a single volume, real-time three-dimensional echocardiography (RT3DE) may facilitate fetal cardiac screening. Methods Four reviewers, each experienced with fetal cardiac imaging, blindly and independently evaluated a single cardiac volume from each of 18 fetuses (11 normal, seven with CHD). Two-dimensional echocardiography served as the gold standard. Three-dimensional evaluation of each fetus included a series of volume acquisitions lasting 2–6 s each. A ‘sweep volume’ technique was developed to fit larger hearts into a single non-gated volume. Results RT3DE had a high sensitivity for detecting CHD (93%), with only a single case being missed by two observers. Specificity for CHD was low (45%), with a high rate of ‘cannot determine’ responses and false positive artifacts. Conclusions These preliminary results suggest that RT3DE has the potential to function as a screening tool for fetal heart disease. However, artifacts must be recognized and minimized, resolution must improve, and substantial training will be necessary prior to widespread clinical use. Copyright © 2005 ISUOG. Published by John Wiley & Sons, Ltd.

Details

ISSN :
09607692
Volume :
25
Database :
OpenAIRE
Journal :
Ultrasound in Obstetrics and Gynecology
Accession number :
edsair.doi...........ed5cbbe5ff7484b7ae497a8055b43ca7
Full Text :
https://doi.org/10.1002/uog.1858