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Real-life use of the eutectic mixture lidocaine/prilocaine spray in men with premature ejaculation
- Source :
- International Journal of Impotence Research. 34:289-294
- Publication Year :
- 2021
- Publisher :
- Springer Science and Business Media LLC, 2021.
-
Abstract
- Topical anaesthetics are considered a first-line therapy option in men with premature ejaculation (PE). A cross-sectional retrospective analysis was performed to evaluate the real-life use of the eutectic mixture of prilocaine/lidocaine spray (FORTACIN™) in a cohort of 198 white-European men who had been consecutively and prospectively seen at a single tertiary-referral andrology centre for self-reported PE and naive for previous PE treatments. Descriptive statistics was used to describe the whole cohort and the paired t-test was applied to investigate potential differences throughout a 12-month follow-up (baseline, 1, 3, 6 and 12 months). Overall, mean (SD) age was 37 (6.5) years. Of all, lifelong, acquired and subjective PE were reported in 101 (51%), 59 (29.8%) and 38 (19.2%) patients at baseline, respectively. FORTACIN™ use increased up to 6 months, with 184 (92.9%) and 128 (66.4%) men who had tried and regularly used the compound, respectively. At 12-month follow-up, 53 (26.8%) men reported a regular use of the compound. Mean Premature Ejaculation Diagnostic Tool score significantly decreased at 6 and 12 months compared to baseline (all p < 0.05). Conversely, mean IELT significantly improved at 6-month follow-up compared to baseline (all p ≤ 0.04). Overall, FORTACIN™ emerged to be a safe and effective treatment option in PE patients of various types, with almost one fourth of patients still under treatment after 12 months. Timing and dosing of the drug can deserve to be adjusted according to patient's needs and their sexual ecology.
- Subjects :
- 030219 obstetrics & reproductive medicine
Lidocaine/prilocaine
Lidocaine
business.industry
Urology
030232 urology & nephrology
Prilocaine
03 medical and health sciences
0302 clinical medicine
Anesthesia
Premature ejaculation
Cohort
medicine
Retrospective analysis
Effective treatment
Dosing
medicine.symptom
business
medicine.drug
Subjects
Details
- ISSN :
- 14765489 and 09559930
- Volume :
- 34
- Database :
- OpenAIRE
- Journal :
- International Journal of Impotence Research
- Accession number :
- edsair.doi...........edc97339af7d243229ad8b0c70cf0a57