Enantio- and diastereomerically pure threo-homoallylic alcohols via highly stereoselective reduction of α-methyl-β,γ-unsaturated ketones

Authors :: Keisuke Suzuki
Gen-ichi Tsuchihashi
Eiji Katayama
Source :: Tetrahedron Letters. 25:2479-2482
Publication Year :: 1984
Publisher :: Elsevier BV, 1984.
Abstract: Reduction of α-methyl-β,γ-unsaturated ketones with L-Selectride proceeded with high threo -selectivity to afford threo -β-methyl homoallylic alcohols of high enantio- and diastereomerical purities.

Subjects :: chemistry.chemical_classification
chemistry.chemical_compound
Ketone
chemistry
Organic Chemistry
Drug Discovery
Chemical reduction
Organic chemistry
Alcohol
Stereoselectivity
Aliphatic compound
Selectivity
Biochemistry

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