ChemInform Abstract: The Synthesis and anti-HIV Activity of Pyrimidine Dioxolanyl Nucleosides

Authors :: Travis Spurling
Woo-Baeg Choi
Phillip A. Furman
Dennis C. Liotta
Deborah L. Cannon
Lawrence J. Wilson
George R. Painter
Raymond F. Schinazi
Marty St. Clair
Source :: ChemInform. 24
Publication Year :: 2010
Publisher :: Wiley, 2010.
Abstract: A series of 5-substituted uracil and cytosine dioxolanyl nucleosides were synthesized as potential anti-HIV agents. Compounds 3a and 3c were found to be extremely in acutely infected human lymphocytes.

Subjects :: Anti hiv activity
chemistry.chemical_compound
chemistry
Pyrimidine
Stereochemistry
Nucleic acid
Uracil
General Medicine
Cytosine

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