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Magnetic targeting of paclitaxel-loaded poly(lactic-co-glycolic acid)-based nanoparticles for the treatment of glioblastoma
- Source :
- International Journal of Nanomedicine. 13:4509-4521
- Publication Year :
- 2018
- Publisher :
- Informa UK Limited, 2018.
-
Abstract
- Introduction Glioblastoma (GBM) therapy is highly challenging, as the tumors are very aggressive due to infiltration into the surrounding normal brain tissue. Even a combination of the available therapeutic regimens may not debulk the tumor completely. GBM tumors are also known for recurrence, resulting in survival rates averaging
- Subjects :
- 0301 basic medicine
Biodistribution
medicine.medical_treatment
Biophysics
Pharmaceutical Science
Bioengineering
02 engineering and technology
Blood–brain barrier
Biomaterials
03 medical and health sciences
chemistry.chemical_compound
In vivo
Drug Discovery
medicine
Chemotherapy
Organic Chemistry
technology, industry, and agriculture
General Medicine
021001 nanoscience & nanotechnology
3. Good health
PLGA
030104 developmental biology
medicine.anatomical_structure
Paclitaxel
chemistry
Cancer research
Nanocarriers
0210 nano-technology
Ex vivo
Subjects
Details
- ISSN :
- 11782013
- Volume :
- 13
- Database :
- OpenAIRE
- Journal :
- International Journal of Nanomedicine
- Accession number :
- edsair.doi...........ef76f1b442dcaeffc6579228eac22b1b
- Full Text :
- https://doi.org/10.2147/ijn.s165184