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Magnetic targeting of paclitaxel-loaded poly(lactic-co-glycolic acid)-based nanoparticles for the treatment of glioblastoma

Authors :
Lakshmi Pallavi Ganipineni
Véronique Préat
Nicolas Joudiou
Bernard Ucakar
John Bianco
Bernard Gallez
Pierre Danhier
Mengnan Zhao
Chiara Bastiancich
Fabienne Danhier
Source :
International Journal of Nanomedicine. 13:4509-4521
Publication Year :
2018
Publisher :
Informa UK Limited, 2018.

Abstract

Introduction Glioblastoma (GBM) therapy is highly challenging, as the tumors are very aggressive due to infiltration into the surrounding normal brain tissue. Even a combination of the available therapeutic regimens may not debulk the tumor completely. GBM tumors are also known for recurrence, resulting in survival rates averaging

Details

ISSN :
11782013
Volume :
13
Database :
OpenAIRE
Journal :
International Journal of Nanomedicine
Accession number :
edsair.doi...........ef76f1b442dcaeffc6579228eac22b1b
Full Text :
https://doi.org/10.2147/ijn.s165184