Survival following TORS for Oropharyngeal SCC

Objective: Report patient characteristics and oncologic results of transoral robotic surgery (TORS) for oropharyngeal squamous cell carcinoma (OPSCC).Method: Retrospective review of 52 patients who underwent TORS with neck dissection and postoperative adjuvant treatment as indicated for OPSCC within a prospective single-arm cohort study at an academic medical center. Tumor stage, human papillomavirus (HPV) status, pathology (margin status, nodal status, extracapsular spread), and survival data were collected.Results: Forty-two patients had HPV testing with 36 patients being HPV positive (85.7%). Most patients presented with advanced stage disease: 40 patients (76.9%) stage IV and 6 patients (11.5%) stage III. Mean length of follow-up was 21 months. Overall survival at 1 and 2 years was 97.9% and 72.7%, respectively, and disease-specific survival at 1 and 2 years was 100% and 84.2%, respectively. There were 2 local recurrences (3.8%), 3 regional recurrences (5.8%), and 2 distant recurrences (3.8%). Subset ...