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Synthesis of 2- and 6-deoxyinositol 1-phosphate and the role of the adjacent hydroxy groups in the mechanism of inositol monophosphatase

Authors :
Nigel J. Liverton
Paul D. Leeson
Janusz Jozef Kulagowski
Raymond Baker
Ian C. Lennon
David C. Billington
Source :
Journal of the Chemical Society, Chemical Communications. :1383
Publication Year :
1989
Publisher :
Royal Society of Chemistry (RSC), 1989.

Abstract

The 2- and 6-hydroxy groups of myo-inositol 1-phosphate have been shown to be independently associated with the mechanisms of hydrolysis and binding in the dephosphorylation of the substrate by inositol monophosphatase.

Details

ISSN :
00224936
Database :
OpenAIRE
Journal :
Journal of the Chemical Society, Chemical Communications
Accession number :
edsair.doi...........f0fa0f2e8bf4c594ca5a42a16b2ef2a3
Full Text :
https://doi.org/10.1039/c39890001383