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Dramatic transient improvement of metastatic BRAFV600E-mutated Langerhans cell sarcoma under treatment with dabrafenib
- Source :
- Blood. 126:2649-2652
- Publication Year :
- 2015
- Publisher :
- American Society of Hematology, 2015.
-
Abstract
- To the editor: Langerhans cell sarcoma (LCS) is a rare histiocytic neoplasm with overt malignant cytological features and an aggressive clinical course.[1][1] Disseminated LCS carries a poor prognosis.[1][1] We report a case of a metastatic BRAF V600E -mutated LCS that dramatically improved after
- Subjects :
- Multimodal imaging
Pathology
medicine.medical_specialty
integumentary system
Immunology
hemic and immune systems
chemical and pharmacologic phenomena
Dabrafenib
Cell Biology
Hematology
Biology
medicine.disease
Biochemistry
BRAF V600E
Histiocytic neoplasm
X ray computed
medicine
Cancer research
Langerhans cell sarcoma
Neoplasm
Vemurafenib
medicine.drug
Subjects
Details
- ISSN :
- 15280020 and 00064971
- Volume :
- 126
- Database :
- OpenAIRE
- Journal :
- Blood
- Accession number :
- edsair.doi...........f11b3b2ca0e600199bb7d146e42ac81d
- Full Text :
- https://doi.org/10.1182/blood-2015-06-650036