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Glucocorticoid receptor PROTACs for the treatment of prostate cancer and other malignancies

Authors :
Yonathan Lissanu Deribe
Philip Jones
James T. Link
Source :
Journal of Clinical Oncology. 36:e14545-e14545
Publication Year :
2018
Publisher :
American Society of Clinical Oncology (ASCO), 2018.

Abstract

e14545Background: Many proteins are difficult to drug, limiting the approaches to treat malignancy. To address the problem, technologies were invented that are not clinically relevant. Proteolysis ...

Details

ISSN :
15277755 and 0732183X
Volume :
36
Database :
OpenAIRE
Journal :
Journal of Clinical Oncology
Accession number :
edsair.doi...........f151df095a985dc6a03e2fd2607e6533