ChemInform Abstract: An Efficient Base-Catalyzed Double Addition of H-Phosphine Oxides to Alkynes

An efficient base-catalyzed double addition of H-phosphine oxides to alkynes is developed. In the presence of a catalytic amount of a base, the addition of various H-phosphine oxides to both aromatic and aliphatic alkynes took place efficiently to produce the corresponding bisphosphoryl compounds in excellent yields. This method provides an easy direct way to prepare bisphosphine oxides that are of high importance in organic synthesis.