Back to Search
Start Over
Proliferation Effects on Hair Growth of Compounds Isolated from the Bark of Dalbergia oliveri
- Source :
- Natural Product Communications. 12:1934578X1701201
- Publication Year :
- 2017
- Publisher :
- SAGE Publications, 2017.
-
Abstract
- One new isoflavane, 7,4′-dihydroxy-isoflavanquinone (1), together with ten known compounds (2–11) were isolated from the bark of Dalbergia oliveri Prain. The structures of compounds were determined on the basis of extensive spectroscopic methods, including 1D and 2D NMR and CD spectroscopic data. Using a cell proliferation assay, the isolated compounds were evaluated for their proliferation effects on hair growth. (3 R)-5’-Methoxyvestitol (2) and (6a R,11a R)-3,8-dihydroxy-9-methoxypterocarpan (10) significantly increased the proliferation of immortalized dermal papilla cells (iDPC).
- Subjects :
- Pharmacology
Traditional medicine
010405 organic chemistry
Plant Science
General Medicine
Fabaceae
Biology
biology.organism_classification
01 natural sciences
0104 chemical sciences
Hair growth
010404 medicinal & biomolecular chemistry
Complementary and alternative medicine
visual_art
Drug Discovery
visual_art.visual_art_medium
Bark
Dalbergia oliveri
Subjects
Details
- ISSN :
- 15559475 and 1934578X
- Volume :
- 12
- Database :
- OpenAIRE
- Journal :
- Natural Product Communications
- Accession number :
- edsair.doi...........f1ddf43ca0730eb0ebab413d80dac433
- Full Text :
- https://doi.org/10.1177/1934578x1701201117