ChemInform Abstract: Diastereoselective Synthesis of Highly Substituted Polycyclic Scaffolds via a One-Pot Four-Step Tandem Catalytic Process

A one-pot four-step multi-reaction process involving a thermal Overman rearrangement, a tandem metathesis reaction, and a Diels—Alder reaction is developed for the diastereoselective synthesis of aminobicyclononanes and -decanes with up to five stereogenic centers.