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Mo1241 Survival Analysis of Antibiotics in Cirrhosis and Esophageal Varices Patients Based on MELD and Childs-Pugh Score

Authors :
Brent A. Neuschwander-Tetri
William Wung
Kara M. Christopher
Diane Ma
Chukwuemeka Ezeoke
Lucy Lin
Source :
Gastroenterology. 148:S-647
Publication Year :
2015
Publisher :
Elsevier BV, 2015.

Abstract

was identified in 30% of subjects. In this group, SBMI and LBMI were strongly correlated with HVPG (r=0.56, p=0.006 and r=0.58, p=0.002 respectively), but not with AST to platelet index (APRI) or FIB-4 scores (r=0.14, p=0.49 and r=0.30, p= 0.15 respectively). In those with viral hepatitis, SBMI and LBMI were not correlated with HVPG values (r=0.16, p=0. 56 and r=0.04, p=0.89), while FIB-4 correlated with HVPG (r=0.71, p=0.002) and APRI trended towards significance (r=0.49, p=0.056).Conclusions: As expected in viral hepatitis, HVPG and non-invasive scoring systems correlated, however spleen and liver volumes did not correlate with HVPG. In NCPH spleen and liver volumes strongly correlated with HVPG, however non-invasive scoring systems did not correlate with HVPG. The finding that spleen and liver volumes may serve as a non-invasive surrogate for portal hypertension in NCPH should be further explored.

Details

ISSN :
00165085
Volume :
148
Database :
OpenAIRE
Journal :
Gastroenterology
Accession number :
edsair.doi...........f2f7321d670b4c8710860afe39e08243
Full Text :
https://doi.org/10.1016/s0016-5085(15)32186-7