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Syntheses of Pantolactone and Pantothenic Acid Derivatives as Potential Lipid Regulating Agents

Authors :
Lianhao Zhang
Ralf Mueller
Michael E. Pape
Andrew McKee
Eelco J. Ebbers
Charles L. Bisgaier
Bruce H. McCosar
Jean-Louis H Dasseux
Clay T. Cramer
Dennis Smith
Mike Relou
Henk Regeling
Emil Pop
B.R. Krause
Frank M. C. Leemhuis
Roel P.L. Bell
Dennis Verdijk
Brian Goetz
Daniela Carmen Oniciu
Source :
Synthetic Communications. 36:365-391
Publication Year :
2006
Publisher :
Informa UK Limited, 2006.

Abstract

A series of pantolactone and pantothenic acid derivatives (1–10) were synthesized to be tested for their potential as lipid regulating agents that act as Coenzyme‐A mimics. The syntheses were performed with moderate to high yields.

Details

ISSN :
15322432 and 00397911
Volume :
36
Database :
OpenAIRE
Journal :
Synthetic Communications
Accession number :
edsair.doi...........f53ca7faef49ee107a23924ef932d1f1
Full Text :
https://doi.org/10.1080/00397910500377545