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Direct N-gem-difluorocyclopropylation of nitro-heterocycles by utilizing gem-difluorocyclopropyl tosylate
- Source :
- Chinese Chemical Letters. 25:24-28
- Publication Year :
- 2014
- Publisher :
- Elsevier BV, 2014.
-
Abstract
- We have developed an efficient method to achieve N-gem-difluorocyclopropylation of N-heterocycles with the use of gem-difluorocyclopropyl tosylate as a building block under mild conditions. gem-Difluorocyclopropyl tosylates could be easily prepared on a large scale and exhibit great stability.
Details
- ISSN :
- 10018417
- Volume :
- 25
- Database :
- OpenAIRE
- Journal :
- Chinese Chemical Letters
- Accession number :
- edsair.doi...........f6115283a5f3a65f0d30f5b8f127d181