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Efficacy of idelalisib in CLL subpopulations harboring del(17p) and other adverse prognostic factors: Results from a phase 3, randomized, double-blind, placebo-controlled trial

Authors :
Bruce D. Cheson
Karl Anton Kreuzer
Eugen Tausch
Mirella Lazarov
Peter Hillmen
Stephan Stilgenbauer
Paolo Ghia
Bertrand Coiffier
Ian W. Flinn
Michael Hallek
Susan O'Brien
John M. Pagel
Jeff Porter Sharman
Wendy Jiang
Richard R. Furman
Andrew D. Zelenetz
Thomas Jahn
Jacqueline C. Barrientos
Steven Coutre
Thomas J. Kipps
Source :
Journal of Clinical Oncology. 32:7011-7011
Publication Year :
2014
Publisher :
American Society of Clinical Oncology (ASCO), 2014.

Abstract

7011^ Background: Idelalisib (IDELA) is a potent and selective inhibitor of PI3Kδ, which is critical for activation, proliferation and survival of B cells and their homing and retention in lymphoid...

Details

ISSN :
15277755 and 0732183X
Volume :
32
Database :
OpenAIRE
Journal :
Journal of Clinical Oncology
Accession number :
edsair.doi...........f790c8618b90bdf2e3dd1deea326325e