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Value of the combination of renal resistance index and central venous pressure in the early prediction of sepsis-induced acute kidney injury
- Source :
- Journal of Critical Care. 45:204-208
- Publication Year :
- 2018
- Publisher :
- Elsevier BV, 2018.
-
Abstract
- Purpose Early prediction of acute kidney injury (AKI) in septic patients is difficult. This study aimed to assess the values of renal resistive index (RI), central venous pressure (CVP), and their combination in the early prediction of sepsis-induced AKI. Methods A prospective cohort study was performed in septic patients. The variables potentially associated with AKI were recorded at admission and compared between the AKI and non-AKI groups. The variables independently associated with sepsis-induced AKI were identified using multivariable logistic regression, and the area under the receiver operating characteristic curve (AUROC) analysis was calculated. Results A total of 124 septic patients were included. Septic shock (OR, 3.28; P = 0.002), high CVP (OR, 1.92; P = 0.012) and renal RI (OR, 2.58; P = 0.009), low diastolic perfusion pressure (DPP) (OR, 2.15; P = 0.010) at admission were independent risk factors for sepsis-induced AKI. The AUROC value of the combination of RI and CVP was greater compared with either RI or CVP alone in predicting sepsis-induced AKI (AUROC = 0.858, 0.811, and 0.780, respectively). Conclusions The combination of RI and CVP was more valuable than either of the two parameters in the early prediction for sepsis-induced AKI.
- Subjects :
- medicine.medical_specialty
Receiver operating characteristic
Septic shock
business.industry
Central venous pressure
Acute kidney injury
Renal function
030208 emergency & critical care medicine
030204 cardiovascular system & hematology
urologic and male genital diseases
Critical Care and Intensive Care Medicine
medicine.disease
female genital diseases and pregnancy complications
Sepsis
03 medical and health sciences
0302 clinical medicine
Internal medicine
Predictive value of tests
medicine
Cardiology
business
Prospective cohort study
Subjects
Details
- ISSN :
- 08839441
- Volume :
- 45
- Database :
- OpenAIRE
- Journal :
- Journal of Critical Care
- Accession number :
- edsair.doi...........f88c951aad79c5d388754cdd1fc508df