Efficacité de l'association hydroxyurée-interféron α dans le traitement des syndromes hyperéosinophiliques (SHE) myéloprolifératifs et/ou résistants à la corticothérapie. Quatre observations

In 4 patients with hypereosinophilic syndrome (3 myeloproliferative and 1 without hematological markers), prednisone and/or hydroxyurea were ineffective. In one case endomyocardial fibrosis progressed and endocardectomy was performed. An interferon α - hydroxyurea combination normalised eosinophilia in 4 cases.