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CD122-selective IL-2 complexes target γδ T and NK cells to reduce tumor-promoting Th17 effects and synergize with αPD-L1 to treat primary and metastatic bladder cancer

Authors :
Ryan Michael Reyes
Yilun Deng
Deyi Zhang
Neelam Mukherjee
Niannian Ji
Karen Wheeler
Harshita B. Gupta
Myrna Garcia
Anand Kornepati
Robert S Svatek
Tyler J Curiel
Source :
The Journal of Immunology. 204:88.14-88.14
Publication Year :
2020
Publisher :
The American Association of Immunologists, 2020.

Abstract

αPD-L1 bladder cancer (BC) immunotherapy is effective in

Subjects

Subjects :
Immunology
Immunology and Allergy

Details

ISSN :
15506606 and 00221767
Volume :
204
Database :
OpenAIRE
Journal :
The Journal of Immunology
Accession number :
edsair.doi...........f9b7efab7b98387a6aaa23e652c44cef
Full Text :
https://doi.org/10.4049/jimmunol.204.supp.88.14