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Antioxidant Capacity of 2-(3,5-diaryl-4,5-dihydro-1H-pyrazol-1-yl)-4-phenylthiazoles
Antioxidant Capacity of 2-(3,5-diaryl-4,5-dihydro-1H-pyrazol-1-yl)-4-phenylthiazoles
- Source :
- Letters in Drug Design & Discovery. 7:657-660
- Publication Year :
- 2010
- Publisher :
- Bentham Science Publishers Ltd., 2010.
-
Abstract
- The antioxidant capacity of 2-(3,5-diaryl-4,5-dihydro-1H-pyrazol-1-yl)-4-phenylthiazoles was evaluated. The values of antioxidant capacities of compounds 2d and 2e were found to be, respectively, 2,700 ± 150 and 3,135 ± 230 TE by the ORAC method, corresponding to a significant antioxidant capacity. recent publication, we reported the antioxidant capacity of phenylpyrazole using the ORAC method (14). In continua- tion of our research program, we report here the antioxidant evaluation of 2-(3,5-diaryl-4,5-dihydro-1H-pyrazol-1-yl)-4- phenylthiazoles, synthetic derivatives compounds of facile preparation (Scheme 1).
Details
- ISSN :
- 15701808
- Volume :
- 7
- Database :
- OpenAIRE
- Journal :
- Letters in Drug Design & Discovery
- Accession number :
- edsair.doi...........fa1b028e30a296ffaa5115aa0d3047c7
- Full Text :
- https://doi.org/10.2174/157018010792929513