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New Indocyanine Derivatives for the Synthesis of Fluorescently Labeled Oligonucleotides

Authors :
Victoria E. Kuznetsova
Edward N. Timofeev
Alexander V. Chudinov
Alexander S. Zasedatelev
Source :
Letters in Organic Chemistry. 6:71-76
Publication Year :
2009
Publisher :
Bentham Science Publishers Ltd., 2009.

Abstract

New sulfonated Cy3 and Cy5 phosphoramidites and solid supports were synthesized. These building blocks were used in the synthesis of terminally or internally labeled oligodeoxynucleotides. Mild deprotection schemes were ap- plied to the sulfocyanine-labeled oligonucleotides.

Details

ISSN :
15701786
Volume :
6
Database :
OpenAIRE
Journal :
Letters in Organic Chemistry
Accession number :
edsair.doi...........fa2d04898e92fa991a1b686e553c8bf6
Full Text :
https://doi.org/10.2174/157017809787003160