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Nanoscale Mo-<formula formulatype='inline'> <tex Notation='TeX'>${\rm MoO}_{3}$</tex> </formula> Entrapped in Engineering Thermoplastic: Inorganic Pathway to Bactericidal and Fungicidal Action
- Source :
- IEEE Transactions on NanoBioscience. 15:258-264
- Publication Year :
- 2016
- Publisher :
- Institute of Electrical and Electronics Engineers (IEEE), 2016.
-
Abstract
- In our contemporary endeavor, metallic molybdenum (Mo) and semiconducting molybdenum trioxide $({\rm MoO}_{3})$ nanostructures have been simultaneously generated via solid state reaction between molybdenum (III) chloride $({\rm MoCl}_{3})$ and polyphenylene sulfide (PPS) at 285 $^{\circ}{\rm C}$ in unimolar ratio for different time durations, namely, 6 h, 24 h, and 48 h. The resultant nanocomposites (NCs) revealed formation of predominantly metallic Mo for all the samples. However, ${\rm MoO}_{3}$ gradually gained prominent position as secondary phase with rise in reaction time. The present study was intended to investigate the antibacterial potential of metal-metal oxide-polymer NCs, i.e., Mo- ${\rm MoO}_{3}$ -PPS against microorganisms, viz., Pseudomonas aeruginosa, Staphylococcus aureus, Klebsiella pneumoniae, and Aspergillus fumigatus. The antibacterial activity of the NCs was evaluated by agar well diffusion investigation. Maximum sensitivity concentrations of NCs were determined by finding out minimum inhibitory concentration (MIC) and minimum bactericidal/fungicidal concentration (MBC/MFC). Moreover, the NCs prepared at reaction time of 48 h exhibited best MBC values and were tested with time kill assay which revealed that the growth of S. aureus was substantially inhibited by Mo- ${\rm MoO}_{3}$ -PPS NCs. This synchronized formation of Mo- ${\rm MoO}_{3}$ nanostructures in an engineering thermoplastic may have potential antimicrobial applications in biomedical devices and components. Prima facie results on antifungal activity are indicative of the fact that these materials can show anti-cancer behavior.
- Subjects :
- Nanostructure
Materials science
Sulfide
Biomedical Engineering
Pharmaceutical Science
Medicine (miscellaneous)
chemistry.chemical_element
Bioengineering
Nanotechnology
02 engineering and technology
010402 general chemistry
01 natural sciences
Chloride
Molybdenum trioxide
Metal
chemistry.chemical_compound
medicine
Electrical and Electronic Engineering
chemistry.chemical_classification
Nanocomposite
021001 nanoscience & nanotechnology
0104 chemical sciences
Computer Science Applications
Crystallography
chemistry
Molybdenum
visual_art
visual_art.visual_art_medium
0210 nano-technology
Antibacterial activity
Biotechnology
medicine.drug
Subjects
Details
- ISSN :
- 15582639 and 15361241
- Volume :
- 15
- Database :
- OpenAIRE
- Journal :
- IEEE Transactions on NanoBioscience
- Accession number :
- edsair.doi...........facb49c6c6b16ab049d079e1b57a45ab