Alternating Layers of Iron(III) Tetra(N-methyl-4-pyridyl)-porphyrin and Copper Tetrasulfonated Phthalocyanine for Amperometric Detection of 4-Nitrophenol in Nanomolar Levels

The present work describes the development of a highly sensitive amperometric sensor for 4-NP in nanomolar levels using a glassy carbon electrode modified with alternating layers of CuTSPc and FeT4MPyP. After optimizing the operational conditions, the sensor provided a linear response range for 4-NP from 5 up to 100 nmol L−1 with sensitivity, detection, and quantification limits of 14 nA L nmol−1, 1.9 nmol L−1, and 5.4 nmol L−1, respectively. The proposed sensor showed a stable response for at least 200 successive determinations. This modified electrode can be used to the determination of 4-NP in water samples.