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A NIR fluorescent probe for the detection of renal damage based on overrepresentation of alanine aminopeptidase enzyme

Authors :
Marcia Domínguez
Kathleen Meyer
Félix Sancenón
Juan F. Blandez
Manuel Serrano
Ramón Martínez-Máñez
Source :
Chemical Communications. 59:2481-2484
Publication Year :
2023
Publisher :
Royal Society of Chemistry (RSC), 2023.

Abstract

Here, we describe the design of a molecular probe (NB-ALA) based on the Nile Blue fluorophore, which can detect alanine aminopeptidase enzyme (a kidney damage biomarker) in urine by simple fluorometric measurements.

Details

ISSN :
1364548X and 13597345
Volume :
59
Database :
OpenAIRE
Journal :
Chemical Communications
Accession number :
edsair.doi...........fc1a86ea9bb6484e5bee4c308402f5bb
Full Text :
https://doi.org/10.1039/d2cc05408f