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A novel ring enlargement: The cyclic expansion of 2-dichloromethyl-2h-pyrroles

Authors :
Augusto Gambacorta
M.L. Forcellese
Rosario Nicoletti
Source :
Tetrahedron. 27:985-990
Publication Year :
1971
Publisher :
Elsevier BV, 1971.

Abstract

Substituted 2-dichloromethyl-2H-pyrroles, when treated with strong bases under appropriate conditions, undergo ring enlargement giving substituted 3-chloropyridines. The data collected on different substrates and reagents indicate the carbenoid nature of intermediate.

Details

ISSN :
00404020
Volume :
27
Database :
OpenAIRE
Journal :
Tetrahedron
Accession number :
edsair.doi...........fc27ce43708af301a57dd824e0d8e5ae
Full Text :
https://doi.org/10.1016/s0040-4020(01)92499-8