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Investigating the scope of pseudoproline assisted peptide cyclization

Authors :
Nima Sayyadi
Katrina A. Jolliffe
Samira Leesch
Deni Taleski
Source :
Tetrahedron. 70:7700-7706
Publication Year :
2014
Publisher :
Elsevier BV, 2014.

Abstract

The cyclization of linear peptides from six to nine amino acids in length and containing between two and four pseudoproline turn inducers derived from serine or threonine was investigated to determine the effect of peptide length, amino acid composition and spacing between the pseudoproline residues on macrocyclization yield.

Details

ISSN :
00404020
Volume :
70
Database :
OpenAIRE
Journal :
Tetrahedron
Accession number :
edsair.doi...........fc62c3261a0fc1733a4e71d21cd8e7b7
Full Text :
https://doi.org/10.1016/j.tet.2014.06.016