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An Endogenous miRNA-Initiated Hybridization Chain Reaction and Subsequent DNAzyme Activation for Cellular Theranostics

Authors :
Jiaoli Wang
Ke Quan
Jin Huang
Jing Li
Kemin Wang
Source :
CCS Chemistry. 4:3505-3515
Publication Year :
2022
Publisher :
Chinese Chemical Society, 2022.

Abstract

DNAzyme has emerged as a promising gene silencer for therapeutic application. However, DNAzyme-based gene therapy against tumors is still restrained by controllable and specific activation in cance...

Details

ISSN :
20965745
Volume :
4
Database :
OpenAIRE
Journal :
CCS Chemistry
Accession number :
edsair.doi...........fcb71d8aa4060d0c0bc713554d294321