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Nanoneuromedicine for management of neurodegenerative disorder

Authors :
Vijay Mishra
Prashant Kesharwani
Murtaza M. Tambuwala
Nitin Dwivedi
Jigna Shah
Source :
Journal of Drug Delivery Science and Technology. 49:477-490
Publication Year :
2019
Publisher :
Elsevier BV, 2019.

Abstract

Conventional drug delivery systems are inadequate in providing essential cyto-architecture restoration and connection patterns because of restrictions posed by the restrictive blood-brain barrier. Nanotechnological approaches involve various nano-sized carrier systems and other devices, which stimulate the action of therapeutic agents on molecular level and revolutionized the treatment and diagnosis of neurodegenerative disorders with minimal side effects. Over the conventional approaches, nanotechnological approaches have various promising strategies to cross blood brain barrier and increase the bioavailability of therapeutics in brain. This review article emphasizes the current and future utility of nano drug delivery systems for the treatment of various neurodegenerative disorders.

Details

ISSN :
17732247
Volume :
49
Database :
OpenAIRE
Journal :
Journal of Drug Delivery Science and Technology
Accession number :
edsair.doi...........fd0c23cb39a1e4a9beec620c6d0909d3
Full Text :
https://doi.org/10.1016/j.jddst.2018.12.021