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Pyrrole-quinazoline derivative as an easily accessible turn-off optical chemosensor for Cu2+ and resultant Cu2+ complex as a turn-on sensor for pyrophosphate in almost neat aqueous solution
- Source :
- Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 226:117592
- Publication Year :
- 2020
- Publisher :
- Elsevier BV, 2020.
-
Abstract
- A simple chemosensor, 6-(1H-pyrrol-2-yl)-5,6-dihydro-benzo[4,5]imidazo[1,2-c]quinazoline (1), was synthesized via simple nucleophilic addition reaction coupled with Schiff base condensation. The probe 1 is aggregation-induced emission-active and could be used as an on–off fluorescence sensor toward Cu2+ in H2O/CH3CN (99.5%, v/v) solution. Furthermore, the resultant Cu2+ complex selectively responded to pyrophosphate (PPi) among various anions based on fluorescent on–off signal. In addition, the probe could be used for detecting Cu2+ and PPi in HeLa cells.
- Subjects :
- Schiff base
Aqueous solution
Nucleophilic addition
02 engineering and technology
010402 general chemistry
021001 nanoscience & nanotechnology
01 natural sciences
Fluorescence
Pyrophosphate
Combinatorial chemistry
Atomic and Molecular Physics, and Optics
0104 chemical sciences
Analytical Chemistry
Turn (biochemistry)
chemistry.chemical_compound
chemistry
Quinazoline
0210 nano-technology
Instrumentation
Spectroscopy
Pyrrole
Subjects
Details
- ISSN :
- 13861425
- Volume :
- 226
- Database :
- OpenAIRE
- Journal :
- Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
- Accession number :
- edsair.doi...........fd427ae3f74e0677485392a3e6d8c93d