Back to Search
Start Over
The study of the possibility of drug dissolution of gallbladder calculi
- Source :
- Sensor Review. 40:363-366
- Publication Year :
- 2020
- Publisher :
- Emerald, 2020.
-
Abstract
- Purpose The purpose of this paper is to verify the possibility of ultrasonic intensification of drug dissolution of cholesterol calculi of the gallbladder using conventional ultrasound frequency and intensity from 0.1 to 0.5 W/cm2. Design/methodology/approach For research purposes, the physical model was developed containing pig bile, pig liver, pigskin, fat and muscles, as well as human cholesterol calculus removed by surgery and a drug with ursodeoxycholic acid. Findings The studies have shown the possibility of accelerating the drug dissolution of calculi of the gallbladder with ultrasound exposure. The ultrasound intensity of 0.4 W/cm2 is the most preferable to intensify the dissolution of calculus. Originality/value The results will be used to advance with development of the device and methodology for ultrasonic intensification of drug dissolution of gallbladder calculi.
- Subjects :
- medicine.medical_specialty
Cholesterol calculus
business.industry
Gallbladder
0206 medical engineering
Ultrasound
Urology
Ultrasound exposure
02 engineering and technology
Conventional ultrasound
020601 biomedical engineering
Industrial and Manufacturing Engineering
Ursodeoxycholic acid
03 medical and health sciences
0302 clinical medicine
medicine.anatomical_structure
medicine
030211 gastroenterology & hepatology
Dissolution testing
Electrical and Electronic Engineering
business
Pig liver
medicine.drug
Subjects
Details
- ISSN :
- 02602288
- Volume :
- 40
- Database :
- OpenAIRE
- Journal :
- Sensor Review
- Accession number :
- edsair.doi...........fea08f4d5a57019ab7fe1c5be5bd50a5