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Echocardiographic findings in patients meeting task force criteria for arrhythmogenic right ventricular dysplasia
- Source :
- Journal of the American College of Cardiology. 45:860-865
- Publication Year :
- 2005
- Publisher :
- Elsevier BV, 2005.
-
Abstract
- Objectives The purpose of this study was to quantify the echocardiographic abnormalities in probands who were newly diagnosed with arrhythmogenic right ventricular dysplasia (ARVD). Background The diagnosis of ARVD remains challenging. The Multidisciplinary Study of Right Ventricular Dysplasia was initiated to characterize the cardiac structural, clinical, and genetic aspects of ARVD. Methods Detailed echocardiograms were performed in 29 probands and compared with echoes from 29 normal control patients matched for age, gender, body size, and year of echo. Right atrial (RA) and right ventricular (RV) chamber dimensions, RV regional function, and the presence of morphologic abnormalities (hyper-reflective moderator band, trabecular derangement, and sacculations) were assessed. The RV systolic function was calculated as RV fractional area change (FAC). Results The RV dimensions were significantly increased, and RV FAC was significantly decreased in probands versus control patients (27.2 ± 16 mm vs. 41.0 ± 7.1 mm, p = 0.0003). The right ventricular outflow tract (RVOT) was the most commonly enlarged dimension in ARVD probands (37.9 ± 6.6 mm) versus control patients (26.2 ± 4.9 mm, p 30 mm occurred in 89% of probands and 14% of controls. The RV morphologic abnormalities were present in many probands (trabecular derangement in 54%, hyper-reflective moderator band in 34% and sacculations in 17%) but not in controls. Conclusions Probands with ARVD have significant RA and RV enlargement and decreased RV function, which can be easily assessed on standard echocardiographic imaging. These parameters should be measured when ARVD is suspected and compared with normal values.
- Subjects :
- Proband
medicine.medical_specialty
Right Ventricular Dysplasia
Heart disease
business.industry
Multidisciplinary study
Sacculation
medicine.disease
Arrhythmogenic right ventricular dysplasia
medicine.anatomical_structure
Internal medicine
medicine
Cardiology
Ventricular outflow tract
Moderator band
Cardiology and Cardiovascular Medicine
business
Subjects
Details
- ISSN :
- 07351097
- Volume :
- 45
- Database :
- OpenAIRE
- Journal :
- Journal of the American College of Cardiology
- Accession number :
- edsair.doi.dedup.....000b20cf0133a720a9bbb188bb281f1d
- Full Text :
- https://doi.org/10.1016/j.jacc.2004.10.070