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Glycemic control and use of glucose-lowering medications in hospital-admitted type 2 diabetes patients over 80 years
- Source :
- Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020), Gotfredsen, D R, Vinther, S, Petersen, T S, Cortes, R, Jensen, T B, Jimenez-Solem, E & Christensen, M B 2020, ' Glycemic control and use of glucose-lowering medications in hospital-admitted type 2 diabetes patients over 80 years ', Scientific Reports, vol. 10, 4095 . https://doi.org/10.1038/s41598-020-60818-5, Scientific Reports
- Publication Year :
- 2020
- Publisher :
- Nature Publishing Group, 2020.
-
Abstract
- Treatment guidelines for type 2 diabetes (T2D) recommend avoidance of hypoglycemia and less stringent glycemic control in older patients. We examined the relation of glycemic control to glucose-lowering medications use in a cohort of patients aged>80 years with a diagnosis of T2D and a hospital admission in the Capital Region of Denmark in 2012–2016. We extracted data on medication use, diagnoses, and biochemistry from the hospitals’ records. We identified 5,172 T2D patients with high degree of co-morbidity and where 17% had an HbA1c in the range recommended for frail, comorbid, older patients with type 2 diabetes (58–75 mmol/mol (7.5–9%)). Half of the patients (n = 2,575) had an HbA1c 1c-values 1c values 1c within the generally recommended glycemic targets. One third of patients did not meet the diagnostic criteria for T2D, and of the patients who were treated with glucose-lowering medications, one-fifth had HbA1c-values suggesting overtreatment.
- Subjects :
- Blood Glucose
Male
medicine.medical_specialty
endocrine system diseases
Epidemiology
lcsh:Medicine
030209 endocrinology & metabolism
Capital region
Type 2 diabetes
Hypoglycemia
Article
03 medical and health sciences
0302 clinical medicine
Patient Admission
Diabetes mellitus
Internal medicine
Medicine
Humans
Hypoglycemic Agents
030212 general & internal medicine
lcsh:Science
Glycemic
Retrospective Studies
Glucose lowering
Aged, 80 and over
Glycated Hemoglobin
Multidisciplinary
business.industry
lcsh:R
nutritional and metabolic diseases
Retrospective cohort study
medicine.disease
Prognosis
Diabetes Mellitus, Type 2
Hyperglycemia
Cohort
Female
lcsh:Q
business
Biomarkers
Follow-Up Studies
Subjects
Details
- Language :
- English
- ISSN :
- 20452322
- Volume :
- 10
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Scientific Reports
- Accession number :
- edsair.doi.dedup.....011ad42c721a502bdb9a20013b151335
- Full Text :
- https://doi.org/10.1038/s41598-020-60818-5