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Glycemic control and use of glucose-lowering medications in hospital-admitted type 2 diabetes patients over 80 years

Authors :
Ditte Resendal Gotfredsen
Siri Vinther
Espen Jimenez-Solem
Thomas Bo Jensen
Mikkel B. Christensen
Tonny Studsgaard Petersen
Rikke Cortes
Source :
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020), Gotfredsen, D R, Vinther, S, Petersen, T S, Cortes, R, Jensen, T B, Jimenez-Solem, E & Christensen, M B 2020, ' Glycemic control and use of glucose-lowering medications in hospital-admitted type 2 diabetes patients over 80 years ', Scientific Reports, vol. 10, 4095 . https://doi.org/10.1038/s41598-020-60818-5, Scientific Reports
Publication Year :
2020
Publisher :
Nature Publishing Group, 2020.

Abstract

Treatment guidelines for type 2 diabetes (T2D) recommend avoidance of hypoglycemia and less stringent glycemic control in older patients. We examined the relation of glycemic control to glucose-lowering medications use in a cohort of patients aged>80 years with a diagnosis of T2D and a hospital admission in the Capital Region of Denmark in 2012–2016. We extracted data on medication use, diagnoses, and biochemistry from the hospitals’ records. We identified 5,172 T2D patients with high degree of co-morbidity and where 17% had an HbA1c in the range recommended for frail, comorbid, older patients with type 2 diabetes (58–75 mmol/mol (7.5–9%)). Half of the patients (n = 2,575) had an HbA1c 1c-values 1c values 1c within the generally recommended glycemic targets. One third of patients did not meet the diagnostic criteria for T2D, and of the patients who were treated with glucose-lowering medications, one-fifth had HbA1c-values suggesting overtreatment.

Details

Language :
English
ISSN :
20452322
Volume :
10
Issue :
1
Database :
OpenAIRE
Journal :
Scientific Reports
Accession number :
edsair.doi.dedup.....011ad42c721a502bdb9a20013b151335
Full Text :
https://doi.org/10.1038/s41598-020-60818-5