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Multichannel nanoplasmonic platform for imidacloprid and fipronil residues rapid screen detection
- Source :
- Biosensorsbioelectronics. 170
- Publication Year :
- 2020
-
Abstract
- In recent years, imidacloprid and fipronil have been reported to harm beneficial insects, such as honey bees, and to potentially pose risks to mammals, including humans. Considering their widespread use and potential minimum toxic range from 10 ppb to 1 ppm (species dependent), a simple, rapid, sensitive, and reliable method for screening and detection is urgently needed. Here, we present a surface plasmon resonance (SPR)-based nanoplasmonic chip integrated with a multichannel spectral imaging system to detect ecosystem-harming pesticides. The pre-modification of the designed mercapto-haptens reduced detection time to 2.5 h. Moreover, owing to the multichannel configuration, it was possible to introduce an internal standard analytical method to effectively reduce matrix interference in real samples; thus, the concentration of the target pesticide could be determined more precisely. The strong linearity of the spiked sample test results indicated high accuracy in quantifying target pesticides. Considering the limit of detection (~10 ppb), the cutoffs for detection and quantification were set at 15 and 45 ppb, respectively, and were used as the detection criteria. The detection results of the blind tests of real samples were also compared with those of liquid chromatography electrospray ionization tandem mass spectrometry (standard method) and were highly consistent. The custom-made integrated SPR system allows much simpler, label-free, high-throughput, and reliable on-site identification and quantification of imidacloprid and fipronil. All test results validated the platform's capability in the on-site rapid screening and detection of pesticide residues at the parts per billion and parts per million levels.
- Subjects :
- medicine.medical_specialty
Biomedical Engineering
Biophysics
02 engineering and technology
Biosensing Techniques
01 natural sciences
chemistry.chemical_compound
Honey Bees
Neonicotinoids
Imidacloprid
Electrochemistry
medicine
Animals
Surface plasmon resonance
Fipronil
Ecosystem
Detection limit
Pesticide residue
010401 analytical chemistry
Pesticide Residues
General Medicine
Pesticide
Bees
021001 nanoscience & nanotechnology
Nitro Compounds
0104 chemical sciences
Spectral imaging
chemistry
Environmental science
Pyrazoles
0210 nano-technology
Biological system
Biotechnology
Subjects
Details
- ISSN :
- 18734235
- Volume :
- 170
- Database :
- OpenAIRE
- Journal :
- Biosensorsbioelectronics
- Accession number :
- edsair.doi.dedup.....012b41384572f0529915e046db160443