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Molecular Imaging of Pulmonary Disease In Vivo
- Source :
- Proceedings of the American Thoracic Society. 6:403-410
- Publication Year :
- 2009
- Publisher :
- American Thoracic Society, 2009.
-
Abstract
- Characterization and noninvasive measurement of molecular pathways and biochemistry in living cells, animal models, and humans at the cellular and molecular level is now possible using remote imaging detectors. Positron and single photon emission tomography scanners, highly sensitive cameras for bioluminescence and fluorescence imaging, as well as high-magnetic-field magnetic resonance imaging scanners, can be used to study such diverse processes as signal transduction, receptor density and function, host response to pathogens, cell trafficking, and gene transfer. In many cases, images from more than one modality can be fused, allowing structure-function and multifunction relationships to be studied on a tissue-restricted or regional basis. "Molecular imaging" holds enormous potential for elucidating the molecular mechanisms of pulmonary disease and therapeutic response in intact animal models and humans.
- Subjects :
- Lung Diseases
Pulmonary and Respiratory Medicine
Fluorescence-lifetime imaging microscopy
Pathology
medicine.medical_specialty
medicine.diagnostic_test
Twenty-Fourth Transatlantic Airway Conference: Imaging Pulmonary Pathology and Target Molecular Signatures
Pulmonary disease
Magnetic resonance imaging
Biology
Magnetic Resonance Imaging
Molecular Imaging
In vivo
Positron emission tomography
Positron-Emission Tomography
Luminescent Measurements
medicine
Humans
Bioluminescence
Signal transduction
Molecular imaging
Neuroscience
Subjects
Details
- ISSN :
- 15463222
- Volume :
- 6
- Database :
- OpenAIRE
- Journal :
- Proceedings of the American Thoracic Society
- Accession number :
- edsair.doi.dedup.....0138bbf414e7d609237018e278fb427c