Identification of three novel avian beta-defensins from goose and their significance in the pathogenesis of Salmonella

Authors :: Kexin Zhang
Deying Ma
Zongxi Han
Shengwang Liu
Mingyue Zhang
Yuhao Shao
Xiaoli Liu
Source :: Molecular Immunology. 56:521-529
Publication Year :: 2013
Publisher :: Elsevier BV, 2013.
Abstract: Here, we report the characterization of three avian β-defensins (AvBDs) from the goose, named anser_AvBD1, AvBD3, and AvBD6, respectively. All of anser_AvBDs exhibited broad antibacterial activity. In addition, the antibacterial activity of all of the AvBDs against Staphylococcus aureus and Proteus mirabilis decreased significantly in the presence of 100mM NaCl (P

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