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Evaluation of oxaliplatin exposure of healthcare workers during heated intraperitoneal perioperative chemotherapy (HIPEC)
- Source :
- ResearcherID, Industrial Health
-
Abstract
- The aim of this study was to evaluate air and surface contaminations, and internal contamination of healthcare workers during open-abdomen HIPEC using oxaliplatin. Platinum (Pt) was measured in urine of exposed workers and in multiple air and surface samples. Three successive HIPEC procedures were investigated in each of the two hospitals participating in the study. Analysis of air samples did not detect any oxaliplatin contamination. Heavy contamination of the operating table, the floor at the surgeon’s feet, and the surgeon’s overshoes were observed. Hand contamination was observed in surgeons using double gloves for intra-abdominal chemotherapy administration, but not in those using three sets of gloves. Pt was not detected in urine samples obtained after HIPEC (
- Subjects :
- Adult
Male
Operating Rooms
medicine.medical_specialty
Organoplatinum Compounds
Health, Toxicology and Mutagenesis
Operating Tables
Regional perfusion
Antineoplastic Agents
Air Pollutants, Occupational
Young Adult
03 medical and health sciences
0302 clinical medicine
Air pollutants
Floors and Floorcoverings
Occupational Exposure
Perioperative chemotherapy
medicine
Humans
Gloves, Surgical
Peritoneal Neoplasms
Surface samples
HIPEC
business.industry
Skin exposure
Public Health, Environmental and Occupational Health
Atmospheric samples
Hyperthermia, Induced
Middle Aged
Contamination
Hand
Shoes
3. Good health
Oxaliplatin
Surgery
Personnel, Hospital
Chemotherapy, Cancer, Regional Perfusion
030220 oncology & carcinogenesis
Biomonitoring
Original Article
Female
030211 gastroenterology & hepatology
Occupational exposure
business
medicine.drug
Subjects
Details
- Database :
- OpenAIRE
- Journal :
- ResearcherID, Industrial Health
- Accession number :
- edsair.doi.dedup.....02a49dd4b57d0672fc6be3fd2486afad