Back to Search
Start Over
CT features of parathyroid carcinomas: comparison with benign parathyroid lesions
- Source :
- Japanese Journal of Radiology. 37:380-389
- Publication Year :
- 2019
- Publisher :
- Springer Science and Business Media LLC, 2019.
-
Abstract
- To describe CT features of parathyroid carcinomas (PCs) by comparison with benign parathyroid lesions (BPs). This retrospective study comprised 82 patients with 76 BPs (62 adenomas and 14 hyperplastic lesions) and 6 PCs. CT features (size, short-to-long axis ratio, shape, peritumoral infiltration, homogeneity, calcification, attenuation values on unenhanced CT, and contrast enhancement during arterial and venous phases) were compared between PCs and BPs. The diagnostic performance of CT features for diagnosing PCs was calculated for these individual parameters. Short-to-long axis ratio was significantly larger in PCs (0.7 ± 0.1) than in BPs (0.5 ± 0.1, p = 0.004). Irregular shape (33%), the presence of peritumoral infiltration (50%), and calcification (33%) were significantly more common in PCs than BPs. The contrast enhancement value was significantly lower in PCs than BPs during arterial (p = 0.004) and venous phases (p = 0.044). The 100% sensitivity criterion for the short-to-long axis ratio (≥ 0.53), enhancement during arterial phase (≤ 56.6HU), and venous phase (≤ 59.5HU) yielded accuracies (62.1%, 71.9%, and 75.4%, respectively). Irregular shape, peritumoral infiltration, and calcification showed high specificity (98.7%) and accuracy (93.9%, 95.1%, and 93.9%, respectively). CT features of high short-to-long axis ratio, irregular shape, the presence of peritumoral infiltration and calcification, and low contrast enhancement may aid in distinguishing PCs from BPs.
- Subjects :
- Adenoma
Adult
Male
Contrast enhancement
Adolescent
Irregular shape
urologic and male genital diseases
Sensitivity and Specificity
030218 nuclear medicine & medical imaging
Diagnosis, Differential
Parathyroid Glands
Young Adult
03 medical and health sciences
0302 clinical medicine
Low contrast
medicine
Humans
Radiology, Nuclear Medicine and imaging
Aged
Retrospective Studies
Parathyroid adenoma
Aged, 80 and over
Hyperplasia
business.industry
Venous phase
Middle Aged
medicine.disease
humanities
Parathyroid Neoplasms
030220 oncology & carcinogenesis
Female
Tomography, X-Ray Computed
business
Nuclear medicine
Infiltration (medical)
hormones, hormone substitutes, and hormone antagonists
Arterial phase
Calcification
Subjects
Details
- ISSN :
- 1867108X and 18671071
- Volume :
- 37
- Database :
- OpenAIRE
- Journal :
- Japanese Journal of Radiology
- Accession number :
- edsair.doi.dedup.....02b8e4803127382e70fdf1cf9b8f43c4