Determinants of Adrenal Androgen Hypofunction in Premenopausal Females With Rheumatoid Arthritis

The aim of our study was to investigate adrenocortical function in the context of disease activity and inflammatory status in premenopausal RA females. Adrenal glucocorticoid and androgen responses to the 1 µg ACTH 1-24 test were investigated in 23 premenopausal RA and in 15 age- and BMI-matched healthy females. Twelve RA patients were on low-dose prednisone (3.2 had lower (p3.2 had lower (p