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Scintigraphic evaluation of reflex sympathetic dystrophy: comparative study of the course of the disease under two therapeutic regimens
- Source :
- Clinical Rheumatology. 6:233-237
- Publication Year :
- 1987
- Publisher :
- Springer Science and Business Media LLC, 1987.
-
Abstract
- A study was made of 26 patients diagnosed as phase I reflex sympathetic dystrophy. In all of them, a bone:soft tissue uptake index was quantified by scintigraphic scanning before treatment and 3 months later. Eighteen patients were treated with 100 MRC units salmon calcitonin, followed by 500 mg elemental calcium 4 hours after hormone administration. The treatment was administered 10 days a month separated by intervals free of therapy. The other 8 patients were treated without interruption with 500 mg naproxen every 12 hours. In the group treated with calcitonin and calcium, the uptake index declined from 13.3 +/- 8.2 to 4.1 +/- 1.8 (p less than 0.001). The uptake index rose from 2.1.3 +/- 17.7 to 31.1 +/- 23.0 (NS) in the naproxen group. Using the Student t-test for paired samples to evaluate individual changes, a highly significant difference was reached (p less than 0.005) in the calcitonin-calcium group. The difference was also significant (p less than 0.01) in the naproxen group, but it was negative (t = 3.620). These results confirm the efficacy of treating reflex sympathetic dystrophy with calcitonin and calcium and the superiority of this treatment as compared with nonsteroidal anti-inflammatory drugs.
- Subjects :
- Adult
Calcitonin
Male
Naproxen
medicine.medical_specialty
Elemental calcium
chemistry.chemical_element
Calcium
Gastroenterology
Bone and Bones
Rheumatology
Internal medicine
medicine
Humans
Radionuclide Imaging
Diphosphonates
business.industry
Technetium
Dystrophy
General Medicine
Middle Aged
Reflex Sympathetic Dystrophy
Technetium Compounds
Endocrinology
chemistry
Reflex
Female
business
Follow-Up Studies
medicine.drug
Hormone
Subjects
Details
- ISSN :
- 14349949 and 07703198
- Volume :
- 6
- Database :
- OpenAIRE
- Journal :
- Clinical Rheumatology
- Accession number :
- edsair.doi.dedup.....03712db96bc5237efa543ac2e318d821