[Studies on single oral doses of a high gel point methylcellulose]

A high gel point methylcellulose (Methocel HG) was given in single doses to normal healthy young adults. Only minor symptoms were reported, e. g., mild laxative effect, mild constipating effect, and a few instances of commonplace symptoms such as cramping, flatus, headache, and tenesmus which apparently were not related to the ingestion of Methocel HG. Essentially all of the ingested Methocel HG was eliminated in the feces within ninety‐six hours following administration.