Chronic Endometritis

Chronic endometritis is a persistent inflammation of the inner lining of the uterine cavity. Several studies have demonstrated that it is a condition frequently associated with repeated unexplained implantation failure at in vitro fertilization, recurrent miscarriage, as well as poor obstetric outcomes such as preterm labor. The aim of this paper is to provide information about diagnosis and treatment of this condition to improve reproductive outcome. In fact, significantly higher rate of successful pregnancies was achieved in those patients in whom antibiotic treatment was able to normalize both hysteroscopic and histologic endometrial pattern compared with women who were not treated or with persistent disease. Hysteroscopy with endometrial biopsy is assumed to be the best method for the detection of chronic endometritis. So, we support the importance of hysteroscopy as a part of the diagnostic workup of infertile women.